KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYRK4
All Species:
20.3
Human Site:
T348
Identified Species:
34.36
UniProt:
Q9NR20
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR20
NP_003836.1
520
59608
T348
K
G
F
P
K
N
I
T
N
N
R
G
K
K
R
Chimpanzee
Pan troglodytes
XP_001158495
520
59654
T348
K
G
F
P
K
T
I
T
N
N
R
G
K
K
R
Rhesus Macaque
Macaca mulatta
XP_001101112
520
59434
L348
M
G
Q
P
K
I
P
L
K
N
H
R
K
L
R
Dog
Lupus familis
XP_534917
565
65190
P392
F
F
D
S
K
G
F
P
K
N
M
T
N
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BI55
632
72542
P459
F
F
D
S
K
G
L
P
K
N
I
N
N
N
R
Rat
Rattus norvegicus
Q4V8A3
586
65492
G404
I
L
A
E
L
L
T
G
Q
P
L
F
P
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509988
466
52101
S295
I
Q
S
R
F
Y
R
S
P
E
V
I
L
G
R
Chicken
Gallus gallus
Q5ZIU3
526
59419
G353
L
L
P
G
E
D
E
G
D
Q
L
A
C
M
I
Frog
Xenopus laevis
Q2TAE3
750
84138
S486
T
N
T
S
N
S
V
S
T
S
P
A
M
E
Q
Zebra Danio
Brachydanio rerio
XP_693389
634
72240
T456
K
G
N
P
R
N
I
T
N
S
K
G
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3D5
722
79590
T442
R
D
A
P
R
C
I
T
N
T
K
G
R
K
R
Honey Bee
Apis mellifera
XP_396369
614
68978
T424
F
G
D
P
R
C
V
T
N
S
K
G
K
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51568
400
46206
P229
E
T
H
F
R
C
L
P
K
S
S
A
I
K
L
Baker's Yeast
Sacchar. cerevisiae
P14680
807
91227
S613
K
L
A
P
E
E
S
S
S
S
T
Q
K
H
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
89.2
76.9
N.A.
65.3
38.7
N.A.
54.2
43.1
28
48.9
N.A.
37.5
42.3
N.A.
N.A.
Protein Similarity:
100
99
91.5
81.2
N.A.
71.5
53.9
N.A.
66.1
59.7
43.3
61.8
N.A.
50.1
59.1
N.A.
N.A.
P-Site Identity:
100
93.3
40
20
N.A.
20
0
N.A.
6.6
0
0
73.3
N.A.
46.6
53.3
N.A.
N.A.
P-Site Similarity:
100
93.3
40
20
N.A.
26.6
0
N.A.
13.3
20
40
93.3
N.A.
73.3
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.8
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.5
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
0
0
0
0
0
0
0
22
0
0
0
% A
% Cys:
0
0
0
0
0
22
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
22
0
0
8
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
0
0
8
15
8
8
0
0
8
0
0
0
8
8
% E
% Phe:
22
15
15
8
8
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
36
0
8
0
15
0
15
0
0
0
36
0
15
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
15
0
0
0
0
8
29
0
0
0
8
8
8
0
8
% I
% Lys:
29
0
0
0
36
0
0
0
29
0
22
0
43
43
0
% K
% Leu:
8
22
0
0
8
8
15
8
0
0
15
0
8
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% M
% Asn:
0
8
8
0
8
15
0
0
36
36
0
8
15
15
0
% N
% Pro:
0
0
8
50
0
0
8
22
8
8
8
0
8
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
8
8
0
8
0
0
8
% Q
% Arg:
8
0
0
8
29
0
8
0
0
0
15
8
8
0
72
% R
% Ser:
0
0
8
22
0
8
8
22
8
36
8
0
0
0
0
% S
% Thr:
8
8
8
0
0
8
8
36
8
8
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
15
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _